Auspicious Tableting Line

Siemens and GEA partner in delivering continuous manufacturing to pharmaceutical industry. Source : GEA

According to the companies, the collaboration will deliver both production benefits, in terms of reduced project execution risk, higher quality and cost-effective manufacturing and customer benefits in the form of seamlessly integrated technologies, expertise and support.

As supplier of process technology and operational systems, GEA has established itself as solution provider in the pharmaceutical industry. The collaboration with Siemens reinforces its global position and now offers life sciences companies an experienced partner to help them implement continuous manufacturing platforms.

Comprising GEA’s continuous manufacturing platform equipped with a Siemens Automation & Industrial IT solution the combined technologies offer both wet granulation and direct compression in a standard-setting solution for continuous tablet production in the pharmaceutical and life sciences industry.

“Amalgamating our state-of-the-art continuous processing technology with Siemens’ automation systems allows us to further support the US Food and Drug Administration’s Pharmaceutical Quality for the 21st Century program and help pharmaceutical companies to adopt continuous manufacturing (CM) technologies and modernize their production infrastructure,” said Frans Maas, Vice President, APC Pharma Solids, GEA. “Together, our combined experience and expertise will provide significant industry benefits as pharmaceutical manufacturers transition towards continuous manufacturing,” he added. “The use of CM technologies and inline PAT monitoring is a key driver of building quality by design (QbD) into the complete product lifecycle, from R&D through to manufacturing, with the ultimate aim of getting safer medicines to market in a more efficient and cost-effective way,” added Hartmut Klocker, Vice President Market Development Board Pharma.

The continuous tableting line is a multipurpose platform that has been designed to transfer powder into coated tablets in development, pilot, clinical and production volumes in a single compact unit. The German based company makes a lot of pledges: the system can perform dosing and mixing of raw materials, wet or dry granulation, drying, tableting, coating and quality control, all in one line. From powder to coated tablet, the novel tableting line allows pharmaceutical companies to continuously process and manufacture oral solid dosage forms. Offering reductions in development time and raw material (API) use, process and energy costs can be considerably decreased using this technology while maintaining quality and increasing manufacturing efficiency.

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